19 October-1 December 2020
The 51st Union World Conference On Lung Health


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EP21-TB as an occupational hazard
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EP21-TB as an occupational hazard
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All E-posters are accessible via the "E-posters" section of the conference platform until 30 November.

EP21-297-23-Comparison of latent TB infections among general vs TB healthcare workers in MyanmarSince healthcare workers are at risk of acquiring tuberculosis (TB) infection, it is important to investigate which type of healthcare workers are at higher risk. This article compared the prevalence of latent TB infections among general healthcare workers against TB healthcare workers and explored the associated factors.
Moe Hnin Phyu

EP21-298-23-Assessing TB case notification among coal miners and their contacts in Balochistan, PakistanIn Balochistan, Pakistan, the first active case finding intervention among coal miners and their contacts was conducted between January and December 2019. It aimed to increase tuberculosis (TB) case detection through three approaches - verbal screening camps, screening through outreach and contact tracing. Patients were diagnosed using Xpert and treatment outcomes documented.  
Kinz ul Eman

EP21-299-23-Reaching the feared, but marginalised, artisanal small-scale miners community with TB servicesZimbabwe is a country endowed with minerals in the great dyke. Large to small scale mining, both formal and informal, are practised. Illegal, informal ASM (artisanal small-scale miners) mining is exacerbated by the escalating economic hardships and high unemployment levels. Its illegality drives marginalisation of health services. TIMS programme intervention has reached the marginalised ASM. 
Donald Dennis Tobaiwa

EP21-300-23-Evaluating the impact of TB infection prevention and control measures in key population wards in South AfricaWe analysed data from the National Health Laboratory Service to understand the impact of administrative controls on case finding in key population wards in South Africa. We observed an overall increase in cases identified in key population wards between pre- and post-intervention periods. This intervention should be scaled further.
Alexander Moran

EP21-301-23-Implementation of TB infection control practices: the case of MalawiTuberculosis (TB) infection prevention and control (IPC) is a key strategy in preventing TB among people living with HIV. In 2015, Malawi National TB Programme revised TB-IPC guidelines. About 850 healthcare workers were trained. N95 masks were procured and distributed to health facilities. Mentorship and support supervision were instituted. We analysed the implementation of TB-IPC practices from 2016-2019.
Henry Kanyerere

EP21-302-23-Strengthening airborne infection control measures in Mumbai health facilities, 2016-2020The COVID-19 pandemic highlights the importance of having infection control practices in place at healthcare facilities (HCFs). SHARE INDIA and Centers for Disease Control and Prevention collaborated with Municipal Corporation of Greater Mumbai to build capacity and strengthen airborne infection control measures in primary and secondary HCF in 10 Mumbai wards.
Satish Kaipilyawar

EP21-303-23-Screening of healthcare workers in Zambia: care of the carers 2018-2019Due to undocumented burden of tuberculosis (TB) among healthcare workers (HCWs), symptomatic TB screening was conducted country-wide. The screening was carried out to determine the burden of TB among HCWs, reduce TB related morbidity and mortality and hospitalisation, as well as help retain a healthy workforce.  
Clara Chola Kasapo

EP21-304-23-Comparing two fit test methods of commonly used N95 respirator in South African healthcare settingsRespiratory protection is a vital component in protecting workers’ health. Although respirators are widely used in healthcare settings, the implementation of a successful respiratory programme has been difficult, particularly in resource-constrained settings like South Africa. Therefore, fit testing of respirators is necessary to screen out poor-fit in respiratory protective equipment.

Katekani Ngobeni

EP21-305-23-Screening of latent TB infection in healthcare workers at a hospital in South Africa using interferon gamma release assay: preliminary findingsIn South Africa, healthcare workers (HCWs) are at greater risk of acquiring tuberculosis (TB) disease than the general population. Surveillance for latent TB infection is important to protect both HCWs and patients.  World Health Organization guidelines recommend regular screening of HCWs in low-incidence settings, however, the feasibility and implementation considerations in high-incidence settings is incompletely understood.
Matsie Mphahlele

EP21-306-23-Yield of TB infection among healthcare workers in Afghanistan: a cross-sectional studyThe yield of tuberculosis (TB) infection and disease among healthcare workers (HCWs) was not known in Afghanistan. We assessed the HCWs using TST and chest X-ray. The findings show higher yield of TB infection and disease among HCWs in Afghanistan and TB infection control must be applied to all healthcare settings.
Ghulam Qader

Channel 2
OA-28-New and old tests for latent TB infection
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OA-28-New and old tests for latent TB infection
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15:00 - 15:05: Introduction

15:05 - 15:13: OA-28-673-23-Systematic review on the diagnostic performance of specific skin test for latent TB infection compared to interferon-gamma release assays and tuberculin skin tests We systematically reviewed the performance of newer skin tests - C-Tb, Diaskintest and ESAT6-CFP10 - for latent tuberculosis infection including 31 previous studies in the data synthesis. Test performance was comparable to the tuberculin skin test and interferon-gamma release assays. Prospective head-to-head diagnostic accuracy studies and longitudinal evaluations are needed.

Maria Krutikov

15:13 - 15:21: OA-28-674-23-An evaluation of community-based TB infection testing using the QuantiFERON-TB Gold Plus assay and preventive treatment linkage in Ho Chi Minh City, Viet Nam Friends for International TB Relief (FIT) piloted the integration of tuberculosis (TB) infection testing using 5,000 QuantiFERON-TB Gold Plus assays at mobile chest X-ray screening events in Ho Chi Minh City, Viet Nam. This analysis examines testing yields, TB preventive treatment linkage using nine months of isoniazid, and treatment outcomes.

Nga Thuy Thi Nguyen

15:21 - 15:29: OA-28-675-23-The magnitude of interferon-gamma release assay response among children with household contact in a high burden setting is associated with TB exposure and active disease The magnitude of IFNy response in children with tuberculosis (TB) household contact correlated with the degree of Mycobacterium tuberculosis (M.tb) exposure using QFT-GIT and T-SPOT.TB. Among contacts ≥2 years, QFT-GIT IFNy levels were significantly higher in children with TB disease compared to children with M.tb infection.

Lena Ronge

15:29 - 15:37: OA-28-676-23-Correlation between monocyte to lymphocyte ratio and tuberculin skin test positivity among antiretroviral treatment-naïve adults Tuberculin skin test (TST) is known to be a barrier to isoniazid preventive therapy implementation. Therefore, alternative tests to assess tuberculosis (TB) risk, such as peripheral blood monocyte to lymphocyte ratio (MLR), have been explored. This study documents the correlation between TST positivity and peripheral MLR in people living with HIV.

Eva Van Ginderdeuren

15:37 - 15:45: OA-28-677-23-Novel strategies for tuberculin skin testing at primary care clinics: an economic evaluation A self-reading, fast-tracking and task-shifting model - combining patient empowerment and differentiated care models - proved to be an innovative, reliable and cost saving approach to tuberculin skin test-guided screening for tuberculosis (TB) preventive therapy in both high and low TB prevalence settings.

Eva Van Ginderdeuren

15:45 - 15:53: OA-28-678-23-TB screening in healthcare workers in Mozambique: where are we? Healthcare workers are a high risk group for tuberculosis (TB) infection. Knowing the burden of TB in this group, it is important to design better strategies towards control and elimination of the disease in this population. Infection control practices are necessary in this population.

Pereira Zindoga

15:53 - 16:01: OA-28-679-23-Identification of barriers and facilitators of TB contact investigation in Cali, Colombia Through a cross-sectional, qualitative study combining human-centred design, social science methods and a knowledge-growing strategy, we conducted different activities with stakeholders to examine their perceptions and lived experiences and, finally, identify barriers to, and facilitators, of tuberculosis (TB) contact investigation in Cali, the third largest Colombian city.

Juan Jiménez-Garcia

16:01 - 16:20: Q&A

Channel 6
SP-40-Implementation and scale-up of TB preventive treatment: overcoming challenges to reach people living with HIV
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SP-40-Implementation and scale-up of TB preventive treatment: overcoming challenges to reach people living with HIV
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The President's Emergency Plan For AIDS Relief (PEPFAR) has committed to providing tuberculosis preventive treatment (TPT) to all people living with HIV (PLHIV) by 2021. Several countries have launched successful TPT surge efforts to achieve this goal and overcome long standing challenges. This session will describe lessons learned from: i) Uganda’s 100-day surge experience where >300,000 PLHIV were initiated on TPT; ii) TPT scale-up in Kenya, which has achieved near universal TPT coverage; iii) TPT scale-up in the context of COVID-19 in Zambia; and iiii) considerations for implementing effective TPT programmes from the World Health Organization.  We will have moderated discussion with our presenters to discuss country-specific questions and challenges from the audience.

16:30 - 16:35: Introduction

16:35 - 16:47: TB preventive treatment scale-up among adults and children living with HIV: best practices from UgandaIn 2019, Uganda established a task force to dramatically scale-up tuberculosis preventive treatment (TPT) through a coordinated, nationwide 100-day campaign to place all eligible adults and children with HIV on TPT. Because of the strong commitment from political leadership and the technical expertise of their task force, from August to October 2019 Uganda initiated 300,000 people on TPT and reached high levels of TPT completion for those initiating.  The Ugandan experience will be shared, including the importance of building the support needed to mobilise the campaign, as well as executing procurement and supply chain logistics during rapid scale-up.  
Deus Lukoye

16:47 - 16:59: TB preventive treatment scale-up among adults and children living with HIV: best practices from KenyaAfter implementing an aggressive TB preventive treatment (TPT) scale-up effort, the number of people receiving TPT in Kenya increased sixty-fold from just under 10,000 in 2014 to more than 600,000 in 2016.  By December 2018, Kenya had provided TPT to 85% of the one million Kenyans receiving antiretroviral treatment. Since 2014, the number of new TB cases among people with HIV has fallen by 40% and Kenya has achieved the highest proportion of eligible children living with HIV receiving TPT in the region, as well as initiating 35% of eligible child contacts under five years of age on TPT, higher than regional averages. The Kenyan approach pairs political will and supply chain innovations, with local action by health facility and community-based health workers, to reach those most vulnerable to TB disease.  This presentation will demonstrate best practices and step-wise implementation guidance for replicating this success.
Christine Wambugu

16:59 - 17:11: TB preventive treatment scale-up in the context of COVID-19: early experiences from ZambiaSince 2017, Zambia has been scaling-up tuberculosis preventive treatment (TPT) among people living with HIV (PLHIV), though challenges with supply chain stymied efforts. In 2018 and 2019, Zambia doubled the number of eligible PLHIV receiving TPT each year, though nearly 75% of eligible PLHIV had yet to complete TPT.  In December 2019, the ministry of health set an ambitious goal of providing TPT to all PLHIV by the end of 2020.  In February 2020, Zambia launched a campaign to rapidly scale-up TPT at high-volume facilities across the country, aiming to initiate 100,000 eligible PLHIV each month.  Just as Phase One of TPT scale-up was underway and achieving early success, COVID-19 caused the ministry of health to abruptly shift course, adjusting screening protocols, scripting intervals, medication delivery, and the pace of its surge. This presentation will provide an overview of these challenges and early experiences with the strategies and approaches used to tailor the response in the midst of COVID-19.
Patrick Lungu

17:11 - 17:23: Considerations for implementing effective TB preventive treatment programmesUptake of tuberculosis preventive treatment (TPT) among people living with HIV (PLHIV) has increased substantially in recent years, especially through the US President’s Emergency Plan for AIDS Relief, which has prioritised TPT as part of routine and comprehensive care for all PLHIV. As part of planning, implementation and scale-up of TPT among PLHIV, more focus and information are needed around how to assure effective and quality programme implementation. Important considerations for TPT programmes include how to develop processes and systems to monitor potential adverse events associated with TPT, how to develop innovative approaches to support treatment adherence and completion, how to engage communities and civil society in creating demand for these services, and how to approach and manage TPT among pregnant women. This presentation will highlight a number of these key considerations to promote quality and effectiveness of TPT programmatic implementation and ensure its desired impact on reducing TB morbidity and mortality.
Avinash Kanchar

17:23 - 17:48: Q&A session

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